Probably.

Vision’s definitely dead, Loki’s probably dead, and Gamora’s either dead or just trapped. But for the ones who got poofed away at the end, most (if not all) are coming back.

Still, we saw them “die” on screen — Spider-Man in particular got a death scene — and haven’t seen them come back yet. It had an emotional impact, and I’m going to treat it as such until something else happens.